Advanced Peptide Technology
Without the Irritation of Retinol
Clinically proven collagen support powered by wound-healing science.
Shop Peptide BestsellersPeptides vs Retinol
Clinically Proven Anti-Aging — Without Irritation
The Traditional Anti-Aging Dilemma
For decades, retinol has been considered the gold standard in anti-aging. But for many women, it comes with redness, peeling, dryness, and sensitivity.
For those with sensitive skin, rosacea, or during pregnancy, retinol often isn’t an option.
Can you smooth wrinkles without irritating your skin?
A Smarter Alternative: Peptide-Powered Repair
Scalisi uses advanced wound-healing technology powered by clinically researched peptides. Our peptides signal the skin to stimulate collagen and hyaluronic acid production naturally.
Instead of irritating the skin to force renewal, we support repair and structural strengthening — reducing visible wrinkles without retinol irritation.
Clinically Proven Results
In clinical testing over 59 days*:
- 45% reduction in area occupied by visible wrinkles
- 37% reduction in wrinkle density
- 15% reduction in wrinkle depth
- 5.5-year rollback in dermal age appearance
*Results may vary.
Advanced Delivery with M/E Technology™
Our proprietary M/E Technology™ mimics advanced drug delivery systems, ensuring active ingredients are efficiently absorbed and distributed throughout the skin.
This is why Scalisi feels like silk — and performs like science.
Consumer-Proven Results
In a 30-day consumer perception study*:
- RADIANT: 94% saw improvement in fine lines, wrinkles, elasticity, and tone in 21 days.
- SPARKLE: 97% said deep wrinkles were less noticeable and crow’s feet diminished in 21 days.
24 women used products twice daily. *Results may vary.