Clinically Proven Peptides. No Retinol Irritation. Made in USA 🇺🇸

Peptides vs Retinol

Advanced Peptide Technology
Without the Irritation of Retinol

Clinically proven collagen support powered by wound-healing science.

Shop Peptide Bestsellers

Peptides vs Retinol

Clinically Proven Anti-Aging — Without Irritation

The Traditional Anti-Aging Dilemma

For decades, retinol has been considered the gold standard in anti-aging. But for many women, it comes with redness, peeling, dryness, and sensitivity.

For those with sensitive skin, rosacea, or during pregnancy, retinol often isn’t an option.

Can you smooth wrinkles without irritating your skin?

A Smarter Alternative: Peptide-Powered Repair

Scalisi uses advanced wound-healing technology powered by clinically researched peptides. Our peptides signal the skin to stimulate collagen and hyaluronic acid production naturally.

Instead of irritating the skin to force renewal, we support repair and structural strengthening — reducing visible wrinkles without retinol irritation.

Peptide Molecular Structure

Clinically Proven Results

In clinical testing over 59 days*:

  • 45% reduction in area occupied by visible wrinkles
  • 37% reduction in wrinkle density
  • 15% reduction in wrinkle depth
  • 5.5-year rollback in dermal age appearance

*Results may vary.

Clinical Results

Advanced Delivery with M/E Technology™

Our proprietary M/E Technology™ mimics advanced drug delivery systems, ensuring active ingredients are efficiently absorbed and distributed throughout the skin.

This is why Scalisi feels like silk — and performs like science.

Product Texture

Consumer-Proven Results

In a 30-day consumer perception study*:

  • RADIANT: 94% saw improvement in fine lines, wrinkles, elasticity, and tone in 21 days.
  • SPARKLE: 97% said deep wrinkles were less noticeable and crow’s feet diminished in 21 days.

24 women used products twice daily. *Results may vary.

Before and After